GJD3

Across TCGA cell cohorts, GJD3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,024 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible GJD3-associated GO terms across cancer lineages are Transcription pausing by RNA polymerase II, Negative regulation of DNA-templated transcription initiation, and Negative regulation of transcription elongation by RNA polymerase II. Each is linked with GJD3 in more than 11 cancer types. Because this analysis shows association rather than direction, both GJD3-to-partner and partner-to-GJD3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Transcription pausing by RNA polymerase II grouped by GJD3-low versus GJD3-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GJD3→partner) and Y-score (partner→GJD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Transcription pausing by RNA polymerase II →	+0.145	+0.689	<.001	<.001	3	12
LARGE_INTESTINE	Negative regulation of DNA-templated transcription initiation →	+0.129	+0.847	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Negative regulation of transcription elongation by RNA polymerase II →	+0.108	+0.840	<.001	.003	3	12
LARGE_INTESTINE	Negative regulation of transcription initiation by RNA polymerase II →	+0.129	+0.847	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Negative regulation of cytoplasmic pattern recognition receptor signaling pathway →	+0.077	+1.001	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Response to epidermal growth factor →	+0.135	+1.050	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,024 associations by consensus.

Transcription pausing by RNA polymerase II by GJD3 expression — BLOOD_Lymphoma

Explore this box plot interactively →