GJD2

Across TCGA patient cohorts, GJD2 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,259 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GJD2-associated proteins across cancer lineages are NPDC1_S236, PURA, and NEFH_S526. Each is linked with GJD2 in more than 2 cancer types. Because this analysis shows association rather than direction, both GJD2-to-partner and partner-to-GJD2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GJD2 versus NPDC1_S236 in GBM, with a Pearson correlation of 0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GJD2→partner) and Y-score (partner→GJD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	NPDC1_S236 →	+1.499	+0.655	<.001	<.001	3	3
GBM	PURA →	+0.415	+0.634	<.001	<.001	3	3
PDAC	NEFH_S526 →	+1.189	+1.213	<.001	<.001	3	3
PDAC	SLC9A3R1_S280 →	-1.287	-1.364	<.001	<.001	3	3
GBM	CHGB_S311 →	+1.046	+0.789	<.001	<.001	3	3
PDAC	CNKSR2_S390 →	+0.617	+0.943	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,259 associations by consensus.

GJD2 vs NPDC1_S236 — GBM

Explore this scatter interactively →