Across TCGA patient cohorts, GJC2 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,696 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GJC2-associated proteins across cancer lineages are DPYSL2, CCNK, and DDX27. Each is linked with GJC2 in more than 5 cancer types. Because this analysis shows association rather than direction, both GJC2-to-partner and partner-to-GJC2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GJC2→partner) and Y-score (partner→GJC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	DPYSL2 →	+0.375	+0.660	<.001	.002	3	6
GBM	CCNK →	-0.226	-0.810	<.001	.002	3	5
LUAD	DDX27 →	-0.296	-0.600	<.001	<.001	3	5
LSCC	ABCF3 →	-0.227	-0.374	<.001	<.001	3	5
GBM	MRPS34 →	-0.368	-1.127	.001	<.001	3	5
LUAD	NOP2 →	-0.397	-0.438	.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,696 associations by consensus.

Exploration

GJC2 survival (RNA) · tumor vs normal (RNA) · all GJC2 data types