Across TCGA patient cohorts, GJC2 protein abundance is significantly associated with the RNA expression of many other genes, with 2,362 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GJC2-associated genes across cancer lineages are PIK3IP1, CRYBB1, and SOX10. Each is linked with GJC2 in more than 1 cancer types. Because this analysis shows association rather than direction, both GJC2-to-partner and partner-to-GJC2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GJC2→partner) and Y-score (partner→GJC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PIK3IP1 →	+0.762	+1.000	<.001	<.001	3	1
GBM	CRYBB1 →	+0.838	+1.219	<.001	<.001	3	1
GBM	SOX10 →	+1.397	+0.976	<.001	<.001	3	1
GBM	PICK1 →	+0.523	+1.114	<.001	<.001	3	1
GBM	SLC16A8 →	+0.503	+0.767	<.001	<.001	3	1
GBM	SUN2 →	+0.333	+0.778	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,362 associations by consensus.

Exploration

GJC2 survival (RNA) · tumor vs normal (RNA) · all GJC2 data types