Across TCGA patient cohorts, GJC2 mutation is significantly associated with the RNA expression of many other genes, with 202 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GJC2-associated genes across cancer lineages are SAMD7, ETFA, and TBR1. Each is linked with GJC2 in more than 1 cancer types. Because this analysis shows association rather than direction, both GJC2-to-partner and partner-to-GJC2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GJC2→partner) and Y-score (partner→GJC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	SAMD7 →	+0.179	+3.107	<.001	.007	3	2
UCEC	ETFA →	+0.819	+3.201	<.001	.009	3	2
COAD	TBR1 →	+0.271	+4.195	<.001	.001	3	2
UCEC	RNU6-379P →	+0.513	+2.694	.001	.005	3	2
UCEC	RNU6-1067P →	+0.390	+2.868	<.001	.006	3	2
UCEC	RNU6-380P →	+0.206	+4.470	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 202 associations by consensus.

Exploration

GJC2 survival (RNA) · tumor vs normal (RNA) · all GJC2 data types