Across TCGA cell cohorts, GJC2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,541 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GJC2-associated GO terms across cancer lineages are Regulation of alternative mRNA splicing, via spliceosome, Regulation of nucleocytoplasmic transport, and mRNA splice site recognition. Each is linked with GJC2 in more than 8 cancer types. Because this analysis shows association rather than direction, both GJC2-to-partner and partner-to-GJC2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GJC2→partner) and Y-score (partner→GJC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Regulation of alternative mRNA splicing, via spliceosome →	+0.088	+0.241	<.001	<.001	3	8
BREAST	Regulation of nucleocytoplasmic transport →	+0.076	+0.488	<.001	.009	2	9
SKIN	mRNA splice site recognition →	+0.079	+0.334	<.001	<.001	3	8
LARGE_INTESTINE	mRNA export from nucleus →	+0.084	+0.634	<.001	.003	2	9
URINARY_TRACT	Protein depolymerization →	+0.102	+0.495	.002	.002	3	8
LUNG_NSCLC_LUSC	Positive regulation of viral life cycle →	+0.175	+0.529	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,541 associations by consensus.

Exploration

GJC2 survival (RNA) · tumor vs normal (RNA) · all GJC2 data types