GJC1

Across TCGA patient cohorts, GJC1 protein abundance is significantly associated with the RNA expression of many other genes, with 1,033 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GJC1-associated genes across cancer lineages are GRAP2, GZMB, and GINS1. Each is linked with GJC1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GJC1-to-partner and partner-to-GJC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GJC1 versus GRAP2 in GBM, with a Pearson correlation of -0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GJC1→partner) and Y-score (partner→GJC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	GRAP2 →	-0.698	-0.573	.005	.002	3	1
GBM	GZMB →	-1.113	-0.516	.006	.003	3	1
GBM	GINS1 →	+0.888	+0.495	<.001	.001	3	1
GBM	UQCC1 →	+0.492	+0.585	.007	.001	3	1
GBM	PABPC1L →	+0.647	+0.559	.008	<.001	3	1
GBM	RAE1 →	+0.338	+0.502	.002	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,033 associations by consensus.

GJC1 vs GRAP2 — GBM

Explore this scatter interactively →