GJB7

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GJB7 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,078 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GJB7-associated proteins across cancer lineages are APEH, NFATC2, and NFKB1. Each is linked with GJB7 in more than 4 cancer types. Because this analysis shows association rather than direction, both GJB7-to-partner and partner-to-GJB7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GJB7 versus APEH in BRCA, with a Pearson correlation of -0.21.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GJB7→partner) and Y-score (partner→GJB7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCAAPEH →-0.350-0.556<.001<.00135
HNSCNFATC2 →-0.368-0.598<.001.00134
GBMNFKB1 →-0.197-0.298<.001<.00134
GBMNONO →+0.198+0.392<.001<.00134
LSCCNUCB1_S369 →-0.587-0.642<.001<.00134
HNSCPM20D2 →+0.498+0.789<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 14,078 associations by consensus.

GJB7 vs APEH — BRCA

Per-sample scatter of GJB7 vs APEH in BRCA (Pearson r = -0.21).

Explore this scatter interactively →

Exploration