GJB7

Across TCGA patient cohorts, GJB7 mutation is significantly associated with the immune_cell of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GJB7-associated genes across cancer lineages are MPP, Osteoblast, and aDC. Each is linked with GJB7 in more than 1 cancer types. Because this analysis shows association rather than direction, both GJB7-to-partner and partner-to-GJB7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MPP grouped by GJB7-low versus GJB7-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GJB7→partner) and Y-score (partner→GJB7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	MPP →	+0.017	+3.995	<.001	.002	3	1
LUAD	Osteoblast →	+0.034	+3.231	.001	.005	3	1
UCEC	aDC →	+0.070	+3.177	.033	.010	3	1
UCEC	Mesangial cells →	-0.051	-3.396	.003	.005	3	1
UCEC	Th1 cells →	+0.084	+2.700	.044	.006	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

MPP by GJB7 expression — LUAD

Explore this box plot interactively →