GJB7

Across TCGA cell cohorts, GJB7 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,398 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible GJB7-associated GO terms across cancer lineages are Positive regulation of microtubule polymerization or depolymerization, Positive regulation of gene expression, epigenetic, and siRNA processing. Each is linked with GJB7 in more than 5 cancer types. Because this analysis shows association rather than direction, both GJB7-to-partner and partner-to-GJB7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of microtubule polymerization or depolymerization grouped by GJB7-low versus GJB7-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GJB7→partner) and Y-score (partner→GJB7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Positive regulation of microtubule polymerization or depolymerization →	+0.070	+0.048	<.001	.009	3	6
LUNG_NSCLC_LUSC	Positive regulation of gene expression, epigenetic →	+0.060	+1.461	<.001	<.001	3	6
LUNG_NSCLC_LUSC	siRNA processing →	+0.129	+1.111	.001	.007	3	6
LUNG_NSCLC_LUSC	Transcription initiation-coupled chromatin remodeling →	+0.081	+1.434	<.001	<.001	3	6
LUNG_NSCLC_LUSC	Gamma-aminobutyric acid signaling pathway →	-0.257	-1.535	<.001	<.001	3	6
STOMACH	Regulation of protein localization to nucleus →	+0.091	+1.268	.001	.004	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,398 associations by consensus.

Positive regulation of microtubule polymerization or depolymerization by GJB7 expression — CNS

Explore this box plot interactively →