GJB6

Across TCGA patient cohorts, GJB6 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,850 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GJB6-associated proteins across cancer lineages are VSNL1, KRT6A, and PKP1_S142. Each is linked with GJB6 in more than 5 cancer types. Because this analysis shows association rather than direction, both GJB6-to-partner and partner-to-GJB6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GJB6 versus VSNL1 in LSCC, with a Pearson correlation of 0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GJB6→partner) and Y-score (partner→GJB6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	VSNL1 →	+1.418	+2.647	<.001	<.001	3	6
PDAC	KRT6A →	+2.094	+1.671	<.001	<.001	3	5
UCEC	PKP1_S142 →	+1.743	+1.542	<.001	.007	3	5
LSCC	KRT17 →	+1.217	+2.306	<.001	<.001	3	5
UCEC	SERPINB5 →	+1.231	+1.239	<.001	.003	3	5
LSCC	AHNAK2_S5175 →	+0.986	+2.006	.002	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,850 associations by consensus.

GJB6 vs VSNL1 — LSCC

Explore this scatter interactively →