Across TCGA patient cohorts, GJB4 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,224 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible GJB4-associated proteins across cancer lineages are LAMB3, LAMC2, and SERPINB5. Each is linked with GJB4 in more than 6 cancer types. Because this analysis shows association rather than direction, both GJB4-to-partner and partner-to-GJB4 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GJB4→partner) and Y-score (partner→GJB4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	LAMB3 →	+0.870	+1.340	<.001	<.001	3	7
HNSC	LAMC2 →	+0.991	+1.097	<.001	<.001	3	6
UCEC	SERPINB5 →	+1.443	+0.799	<.001	<.001	3	5
UCEC	BCAR1 →	+0.281	+0.755	<.001	<.001	3	5
LSCC	AHNAK2 →	+0.960	+1.091	<.001	.002	3	5
HNSC	AHNAK2_S260 →	+1.126	+1.287	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,224 associations by consensus.

Exploration

GJB4 survival (RNA) · tumor vs normal (RNA) · all GJB4 data types