GJA9

Across TCGA patient cohorts, GJA9 mutation is significantly associated with the RNA expression of many other genes, with 1,906 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GJA9-associated genes across cancer lineages are RNU6-788P, RPL36P18, and RPL31P59. Each is linked with GJA9 in more than 2 cancer types. Because this analysis shows association rather than direction, both GJA9-to-partner and partner-to-GJA9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-788P grouped by GJA9-low versus GJA9-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GJA9→partner) and Y-score (partner→GJA9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	RNU6-788P →	+0.446	+7.336	<.001	<.001	3	3
SKCM	RPL36P18 →	+0.132	+3.661	<.001	.009	3	2
LUSC	RPL31P59 →	+0.315	+4.211	<.001	.009	3	2
SKCM	MIR6729 →	+0.314	+4.884	<.001	.004	3	2
LUAD	OR4D5 →	+0.750	+6.315	<.001	.001	3	2
UCEC	RNU1-17P →	+0.224	+2.613	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,906 associations by consensus.

RNU6-788P by GJA9 expression — LUSC

Explore this box plot interactively →