GJA9

Across TCGA cell cohorts, GJA9 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,127 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible GJA9-associated GO terms across cancer lineages are Cilium or flagellum-dependent cell motility, Cilium-dependent cell motility, and Cilium movement involved in cell motility. Each is linked with GJA9 in more than 10 cancer types. Because this analysis shows association rather than direction, both GJA9-to-partner and partner-to-GJA9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cilium or flagellum-dependent cell motility grouped by GJA9-low versus GJA9-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GJA9→partner) and Y-score (partner→GJA9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Cilium or flagellum-dependent cell motility →	-0.042	-0.196	.001	<.001	3	11
LUNG_NSCLC_LUAD	Cilium-dependent cell motility →	-0.042	-0.196	.001	<.001	3	11
LUNG_NSCLC_LUAD	Cilium movement involved in cell motility →	-0.061	-0.250	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Negative regulation of autophagy →	+0.057	+0.184	.004	.001	3	10
UPPER_AERODIGESTIVE_TRACT	Proteasomal ubiquitin-independent protein catabolic process →	+0.074	+0.229	.002	.009	3	9
UPPER_AERODIGESTIVE_TRACT	Cellular response to nutrient levels →	+0.039	+0.210	.009	.003	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,127 associations by consensus.

Cilium or flagellum-dependent cell motility by GJA9 expression — LUNG_NSCLC_LUAD

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