GJA9

Across TCGA cell cohorts, GJA9 mutation is significantly associated with the mutation status of many other genes, with 3,426 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GJA9-associated genes across cancer lineages are GUCY2F, SIGLEC8, and DNMBP. Each is linked with GJA9 in more than 1 cancer types. Because this analysis shows association rather than direction, both GJA9-to-partner and partner-to-GJA9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GUCY2F grouped by GJA9-low versus GJA9-high in STOMACH.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GJA9→partner) and Y-score (partner→GJA9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	GUCY2F →	+4.807	+4.807	.008	.008	1	2
LARGE_INTESTINE	SIGLEC8 →	+2.321	+2.321	.003	.003	1	2
LARGE_INTESTINE	DNMBP →	+1.906	+2.050	.009	.009	1	2
LARGE_INTESTINE	EHD3 →	+3.906	+3.000	<.001	<.001	1	2
STOMACH	VSIG10L →	+4.807	+4.807	.008	.008	1	2
STOMACH	C17orf97 →	+4.807	+4.807	.008	.008	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,426 associations by consensus.

GUCY2F by GJA9 expression — STOMACH

Explore this box plot interactively →