GJA5

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GJA5 protein abundance is significantly associated with the RNA expression of many other genes, with 9,494 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GJA5-associated genes across cancer lineages are CDCA7L, DLG2-AS2, and SNRPD3. Each is linked with GJA5 in more than 2 cancer types. Because this analysis shows association rather than direction, both GJA5-to-partner and partner-to-GJA5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GJA5 versus CDCA7L in LSCC, with a Pearson correlation of -0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GJA5→partner) and Y-score (partner→GJA5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCCDCA7L →-1.003-0.545<.001<.00133
LUADDLG2-AS2 →+0.543+0.533<.001<.00133
LSCCSNRPD3 →-0.584-0.541<.001<.00132
LSCCCYTH4 →+0.771+0.524<.001<.00132
LSCCSNU13 →-0.373-0.467<.001<.00132
LSCCCSF2RB →+0.933+0.601<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 9,494 associations by consensus.

GJA5 vs CDCA7L — LSCC

Per-sample scatter of GJA5 vs CDCA7L in LSCC (Pearson r = -0.39).

Explore this scatter interactively →

Exploration