GJA5

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, GJA5 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,402 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible GJA5-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Negative regulation of syncytium formation by plasma membrane fusion, and Stress granule assembly. Each is linked with GJA5 in more than 8 cancer types. Because this analysis shows association rather than direction, both GJA5-to-partner and partner-to-GJA5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by GJA5-low versus GJA5-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GJA5→partner) and Y-score (partner→GJA5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STOMACHNegative regulation of myoblast fusion →+0.079+0.887.006.00339
STOMACHNegative regulation of syncytium formation by plasma membrane fusion →+0.077+0.894.007.00339
BLOOD_LymphomaStress granule assembly →+0.068+0.023.001.00538
STOMACHProtein stabilization →+0.076+1.573<.001.00238
STOMACHmRNA transport →+0.078+0.889.001.00338
SKINBlood coagulation, fibrin clot formation →+0.151+1.469.005<.00138
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,402 associations by consensus.

Negative regulation of myoblast fusion by GJA5 expression — STOMACH

Box plot of Negative regulation of myoblast fusion in GJA5-low vs GJA5-high samples in STOMACH.

Explore this box plot interactively →

Exploration