Across TCGA patient cohorts, GJA4 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,626 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GJA4-associated proteins across cancer lineages are NID1, NID2, and LAMA4. Each is linked with GJA4 in more than 7 cancer types. Because this analysis shows association rather than direction, both GJA4-to-partner and partner-to-GJA4 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GJA4→partner) and Y-score (partner→GJA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	NID1 →	+0.446	+1.198	<.001	<.001	3	8
GBM	NID2 →	+0.654	+0.641	<.001	<.001	3	8
CCRCC	LAMA4 →	+0.488	+1.136	<.001	<.001	3	8
CCRCC	LAMB1 →	+0.539	+1.432	<.001	<.001	3	7
GBM	LAMC1 →	+0.692	+0.598	<.001	<.001	3	7
CCRCC	MMRN2 →	+0.749	+1.501	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,626 associations by consensus.

Exploration

GJA4 survival (RNA) · tumor vs normal (RNA) · all GJA4 data types