Across TCGA cell cohorts, GJA4 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,346 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GJA4-associated GO terms across cancer lineages are Regulation of mRNA processing, Regulation of ubiquitin-dependent protein catabolic process, and Negative regulation of syncytium formation by plasma membrane fusion. Each is linked with GJA4 in more than 8 cancer types. Because this analysis shows association rather than direction, both GJA4-to-partner and partner-to-GJA4 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GJA4→partner) and Y-score (partner→GJA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Regulation of mRNA processing →	+0.038	+0.053	.006	.008	3	9
UPPER_AERODIGESTIVE_TRACT	Regulation of ubiquitin-dependent protein catabolic process →	+0.052	+0.073	.001	.004	3	7
UPPER_AERODIGESTIVE_TRACT	Negative regulation of syncytium formation by plasma membrane fusion →	+0.128	+0.108	<.001	<.001	3	7
LUNG_NSCLC_LUAD	Regulation of nucleocytoplasmic transport →	+0.053	+0.066	<.001	<.001	3	7
BLOOD_Lymphoma	Viral process →	+0.044	+0.041	<.001	<.001	2	8
UPPER_AERODIGESTIVE_TRACT	Response to misfolded protein →	+0.061	+0.070	.004	.008	2	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,346 associations by consensus.

Exploration

GJA4 survival (RNA) · tumor vs normal (RNA) · all GJA4 data types