GIT2

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GIT2 protein abundance is significantly associated with the RNA expression of many other genes, with 17,385 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GIT2-associated genes across cancer lineages are RASAL3, PIK3CG, and BTK. Each is linked with GIT2 in more than 8 cancer types. Because this analysis shows association rather than direction, both GIT2-to-partner and partner-to-GIT2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GIT2 versus RASAL3 in LSCC, with a Pearson correlation of 0.76.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GIT2→partner) and Y-score (partner→GIT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCRASAL3 →+0.954+0.307<.001<.00139
LSCCPIK3CG →+1.109+0.366<.001<.00139
OVBTK →+1.066+0.260.002<.00139
HNSCABI3 →+1.205+0.309<.001<.00139
OVCRTAM →+0.708+0.262<.001<.00139
COADMS4A6A →+1.166+0.219<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 17,385 associations by consensus.

GIT2 vs RASAL3 — LSCC

Per-sample scatter of GIT2 vs RASAL3 in LSCC (Pearson r = 0.76).

Explore this scatter interactively →

Exploration