GIT2

Across TCGA cell cohorts, GIT2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,171 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible GIT2-associated GO terms across cancer lineages are Positive regulation of pinocytosis, Nuclear transport, and Nucleocytoplasmic transport. Each is linked with GIT2 in more than 15 cancer types. Because this analysis shows association rather than direction, both GIT2-to-partner and partner-to-GIT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of pinocytosis grouped by GIT2-low versus GIT2-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GIT2→partner) and Y-score (partner→GIT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Positive regulation of pinocytosis →	+0.132	+0.813	.007	.009	3	16
STOMACH	Nuclear transport →	+0.076	+0.898	.004	.003	3	16
STOMACH	Nucleocytoplasmic transport →	+0.077	+0.898	.004	.003	3	16
BREAST	Positive regulation of telomere maintenance →	+0.061	+0.547	.001	.002	3	16
UPPER_AERODIGESTIVE_TRACT	Phosphatidylinositol metabolic process →	+0.057	+1.098	<.001	<.001	3	16
SOFT_TISSUE	Nuclear export →	+0.092	+1.070	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,171 associations by consensus.

Positive regulation of pinocytosis by GIT2 expression — STOMACH

Explore this box plot interactively →