GIT1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GIT1 protein abundance is significantly associated with the RNA expression of many other genes, with 14,849 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GIT1-associated genes across cancer lineages are ANKRD13B, GOSR1, and SUZ12P1. Each is linked with GIT1 in more than 6 cancer types. Because this analysis shows association rather than direction, both GIT1-to-partner and partner-to-GIT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GIT1 versus ANKRD13B in LSCC, with a Pearson correlation of 0.53.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GIT1→partner) and Y-score (partner→GIT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCANKRD13B →+1.091+0.188<.001<.00137
LSCCGOSR1 →+0.479+0.207<.001<.00137
LSCCSUZ12P1 →+0.734+0.192<.001<.00136
LSCCTADA2A →+0.629+0.209<.001<.00136
LSCCC17orf75 →+0.686+0.193<.001<.00136
BRCAEZH1 →+0.507+0.189<.001.00136
Each partner links to its Q-omics profile. Showing the 6 strongest of 14,849 associations by consensus.

GIT1 vs ANKRD13B — LSCC

Per-sample scatter of GIT1 vs ANKRD13B in LSCC (Pearson r = 0.53).

Explore this scatter interactively →

Exploration