GIT1

Across TCGA cell cohorts, GIT1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,907 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GIT1-associated GO terms across cancer lineages are Nuclear export, Nucleosome disassembly, and Pre-mRNA catabolic process. Each is linked with GIT1 in more than 12 cancer types. Because this analysis shows association rather than direction, both GIT1-to-partner and partner-to-GIT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nuclear export grouped by GIT1-low versus GIT1-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GIT1→partner) and Y-score (partner→GIT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Nuclear export →	+0.080	+0.984	<.001	<.001	3	13
BONE	Nucleosome disassembly →	+0.230	+1.367	<.001	<.001	3	13
KIDNEY	Pre-mRNA catabolic process →	+0.154	+0.835	<.001	.006	3	13
BONE	Protein-DNA complex disassembly →	+0.196	+1.404	<.001	<.001	3	13
BONE	Regulation of G0 to G1 transition →	+0.145	+1.227	<.001	<.001	3	12
BONE	Regulation of nucleotide-excision repair →	+0.121	+1.069	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,907 associations by consensus.

Nuclear export by GIT1 expression — LARGE_INTESTINE

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