GIPR

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GIPR protein abundance is significantly associated with the RNA expression of many other genes, with 1,708 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible GIPR-associated genes across cancer lineages are LMO7, ZEB2, and PPIH. Each is linked with GIPR in more than 1 cancer types. Because this analysis shows association rather than direction, both GIPR-to-partner and partner-to-GIPR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GIPR versus LMO7 in LUAD, with a Pearson correlation of -0.64.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GIPR→partner) and Y-score (partner→GIPR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUADLMO7 →-1.535-0.866<.001.00732
BRCAZEB2 →-0.979-0.647.002.00232
BRCAPPIH →+0.845+0.747.002.00632
BRCASELENOP →-2.024-0.846.006.00232
LUADRPL10P13 →+2.665+0.916<.001<.00132
LUADSUSD2 →-3.429-0.741<.001.00932
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,708 associations by consensus.

GIPR vs LMO7 — LUAD

Per-sample scatter of GIPR vs LMO7 in LUAD (Pearson r = -0.64).

Explore this scatter interactively →

Exploration