GIPC3

Across TCGA patient cohorts, GIPC3 mutation is significantly associated with the RNA expression of many other genes, with 6,446 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GIPC3-associated genes across cancer lineages are RNA5SP412, PGAM3P, and HNRNPA1P29. Each is linked with GIPC3 in more than 2 cancer types. Because this analysis shows association rather than direction, both GIPC3-to-partner and partner-to-GIPC3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP412 grouped by GIPC3-low versus GIPC3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GIPC3→partner) and Y-score (partner→GIPC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP412 →	+0.395	+1.671	<.001	.001	3	3
COAD	PGAM3P →	+0.150	+3.973	<.001	.008	3	3
CESC	HNRNPA1P29 →	+0.035	+3.345	<.001	.008	3	2
CESC	LINC02559 →	+0.749	+4.020	<.001	.009	3	2
CESC	LINC02380 →	+0.122	+3.345	<.001	.008	3	2
CESC	MIR4510 →	+0.165	+4.020	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,446 associations by consensus.

RNA5SP412 by GIPC3 expression — UCEC

Explore this box plot interactively →