GIPC1

Across TCGA patient cohorts, GIPC1 mutation is significantly associated with the immune_cell of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GIPC1-associated genes across cancer lineages are CD8+ T-cells, CD8+ Tcm, and Astrocytes. Each is linked with GIPC1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GIPC1-to-partner and partner-to-GIPC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD8+ T-cells grouped by GIPC1-low versus GIPC1-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GIPC1→partner) and Y-score (partner→GIPC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CD8+ T-cells →	+0.084	+5.015	<.001	.009	3	2
HNSC	CD8+ Tcm →	+0.088	+3.813	<.001	.042	3	2
UCEC	Astrocytes →	-0.038	-2.020	.044	.041	3	1
UCEC	mv Endothelial cells →	-0.021	-2.459	.027	.020	3	1
UCEC	Plasma cells →	-0.025	-3.346	.005	.005	2	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

CD8+ T-cells by GIPC1 expression — HNSC

Explore this box plot interactively →