GIP

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GIP mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GIP-associated genes across cancer lineages are CD4+ Tcm and Fibroblasts. Each is linked with GIP in more than 1 cancer types. Because this analysis shows association rather than direction, both GIP-to-partner and partner-to-GIP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD4+ Tcm grouped by GIP-low versus GIP-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GIP→partner) and Y-score (partner→GIP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCACD4+ Tcm →+0.013+6.725.014.01831
UCECFibroblasts →+0.055+3.978.004.01431
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

CD4+ Tcm by GIP expression — BRCA

Box plot of CD4+ Tcm in GIP-low vs GIP-high samples in BRCA.

Explore this box plot interactively →

Exploration