GINS2

Across TCGA patient cohorts, GINS2 protein abundance is significantly associated with the RNA expression of many other genes, with 15,406 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GINS2-associated genes across cancer lineages are GINS1, ZNF367, and CENPM. Each is linked with GINS2 in more than 7 cancer types. Because this analysis shows association rather than direction, both GINS2-to-partner and partner-to-GINS2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GINS2 versus GINS1 in UCEC, with a Pearson correlation of 0.53.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GINS2→partner) and Y-score (partner→GINS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GINS1 →	+1.144	+0.632	<.001	<.001	3	8
GBM	ZNF367 →	+1.007	+0.750	.001	<.001	3	8
UCEC	CENPM →	+1.080	+0.375	.001	<.001	3	7
HNSC	MCM5 →	+1.013	+0.524	<.001	<.001	3	7
UCEC	CDKN3 →	+1.126	+0.582	<.001	<.001	3	7
LSCC	VRK1 →	+0.729	+0.641	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,406 associations by consensus.

GINS2 vs GINS1 — UCEC

Explore this scatter interactively →