GINS2

Across TCGA cell cohorts, GINS2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,477 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible GINS2-associated GO terms across cancer lineages are Mitotic DNA replication, Nuclear DNA replication, and Cell cycle DNA replication. Each is linked with GINS2 in more than 19 cancer types. Because this analysis shows association rather than direction, both GINS2-to-partner and partner-to-GINS2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitotic DNA replication grouped by GINS2-low versus GINS2-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GINS2→partner) and Y-score (partner→GINS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Mitotic DNA replication →	+0.204	+1.361	<.001	<.001	3	20
UPPER_AERODIGESTIVE_TRACT	Nuclear DNA replication →	+0.160	+1.850	<.001	<.001	3	20
UPPER_AERODIGESTIVE_TRACT	Cell cycle DNA replication →	+0.163	+1.967	<.001	<.001	3	20
BONE	DNA replication initiation →	+0.260	+1.610	<.001	<.001	3	20
STOMACH	Double-strand break repair via break-induced replication →	+0.235	+1.825	<.001	<.001	3	20
BONE	DNA-templated DNA replication →	+0.135	+1.252	.001	.001	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,477 associations by consensus.

Mitotic DNA replication by GINS2 expression — BLOOD_Myeloma

Explore this box plot interactively →