GINS1

Across TCGA patient cohorts, GINS1 protein abundance is significantly associated with the RNA expression of many other genes, with 11,533 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GINS1-associated genes across cancer lineages are FANCI, ESCO2, and FANCB. Each is linked with GINS1 in more than 5 cancer types. Because this analysis shows association rather than direction, both GINS1-to-partner and partner-to-GINS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GINS1 versus FANCI in GBM, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GINS1→partner) and Y-score (partner→GINS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	FANCI →	+0.913	+0.663	.001	.003	3	6
GBM	ESCO2 →	+0.932	+0.668	.001	<.001	3	6
LSCC	FANCB →	+1.079	+0.845	<.001	<.001	3	6
GBM	CDKN3 →	+1.024	+0.590	<.001	<.001	3	5
GBM	CENPI →	+0.974	+0.711	<.001	<.001	3	5
UCEC	NCAPG →	+1.024	+0.447	<.001	.003	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,533 associations by consensus.

GINS1 vs FANCI — GBM

Explore this scatter interactively →