GINS1

Across TCGA cell cohorts, GINS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,207 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GINS1-associated GO terms across cancer lineages are Nuclear DNA replication, Cell cycle DNA replication, and DNA strand elongation involved in DNA replication. Each is linked with GINS1 in more than 19 cancer types. Because this analysis shows association rather than direction, both GINS1-to-partner and partner-to-GINS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nuclear DNA replication grouped by GINS1-low versus GINS1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GINS1→partner) and Y-score (partner→GINS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Nuclear DNA replication →	+0.241	+1.701	<.001	<.001	3	20
BONE	Cell cycle DNA replication →	+0.172	+1.416	<.001	<.001	3	20
SOFT_TISSUE	DNA strand elongation involved in DNA replication →	+0.194	+1.061	<.001	<.001	3	20
BONE	Mitotic chromosome condensation →	+0.231	+1.657	<.001	.001	3	20
BONE	Mitotic DNA replication →	+0.261	+1.591	<.001	.002	3	19
UPPER_AERODIGESTIVE_TRACT	Interstrand cross-link repair →	+0.105	+1.942	<.001	<.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,207 associations by consensus.

Nuclear DNA replication by GINS1 expression — BONE

Explore this box plot interactively →