GINM1

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GINM1 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GINM1-associated genes across cancer lineages are aDC and Th2 cells. Each is linked with GINM1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GINM1-to-partner and partner-to-GINM1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, aDC grouped by GINM1-low versus GINM1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GINM1→partner) and Y-score (partner→GINM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECaDC →+0.087+2.180.024.03632
UCECTh2 cells →+0.273+3.010.003.01932
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

aDC by GINM1 expression — UCEC

Box plot of aDC in GINM1-low vs GINM1-high samples in UCEC.

Explore this box plot interactively →

Exploration