GIN1

Across TCGA cell cohorts, GIN1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,873 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GIN1-associated GO terms across cancer lineages are Protein localization to cilium, Negative regulation of G2/M transition of mitotic cell cycle, and NAD-cap decapping. Each is linked with GIN1 in more than 9 cancer types. Because this analysis shows association rather than direction, both GIN1-to-partner and partner-to-GIN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to cilium grouped by GIN1-low versus GIN1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GIN1→partner) and Y-score (partner→GIN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Protein localization to cilium →	+0.074	+0.901	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Negative regulation of G2/M transition of mitotic cell cycle →	+0.098	+0.730	.001	.002	3	10
UPPER_AERODIGESTIVE_TRACT	NAD-cap decapping →	+0.096	+0.670	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Positive regulation of maintenance of sister chromatid cohesion →	+0.069	+0.743	.007	.003	3	10
UPPER_AERODIGESTIVE_TRACT	Positive regulation of maintenance of mitotic sister chromatid cohesion →	+0.069	+0.743	.007	.003	3	10
UPPER_AERODIGESTIVE_TRACT	Protein localization to chromosome →	+0.110	+0.747	.003	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,873 associations by consensus.

Protein localization to cilium by GIN1 expression — UPPER_AERODIGESTIVE_TRACT

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