GIMAP8

Across TCGA patient cohorts, GIMAP8 protein abundance is significantly associated with the RNA expression of many other genes, with 19,064 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GIMAP8-associated genes across cancer lineages are GZMB, LILRA1, and ST8SIA4. Each is linked with GIMAP8 in more than 9 cancer types. Because this analysis shows association rather than direction, both GIMAP8-to-partner and partner-to-GIMAP8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GIMAP8 versus GZMB in BRCA, with a Pearson correlation of 0.64.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GIMAP8→partner) and Y-score (partner→GIMAP8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	GZMB →	+1.702	+0.455	<.001	<.001	3	10
HNSC	LILRA1 →	+0.654	+0.577	<.001	<.001	3	10
GBM	ST8SIA4 →	+0.911	+0.612	<.001	<.001	3	10
BRCA	S1PR4 →	+1.040	+0.548	<.001	<.001	3	10
UCEC	GMFG →	+1.192	+0.717	<.001	<.001	3	10
OV	GIMAP6 →	+1.124	+0.547	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,064 associations by consensus.

GIMAP8 vs GZMB — BRCA

Explore this scatter interactively →