GIMAP8

Across TCGA cell cohorts, GIMAP8 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,072 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GIMAP8-associated GO terms across cancer lineages are Response to superoxide, Putrescine biosynthetic process, and Post-embryonic development. Each is linked with GIMAP8 in more than 3 cancer types. Because this analysis shows association rather than direction, both GIMAP8-to-partner and partner-to-GIMAP8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to superoxide grouped by GIMAP8-low versus GIMAP8-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GIMAP8→partner) and Y-score (partner→GIMAP8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Response to superoxide →	+0.075	+0.844	<.001	.009	3	4
BLOOD_Lymphoma	Putrescine biosynthetic process →	-0.102	-0.759	<.001	.001	3	4
KIDNEY	Post-embryonic development →	+0.072	+0.031	.005	.003	3	4
LUNG_NSCLC_LUAD	T-helper 17 type immune response →	+0.117	+0.010	.003	.004	3	3
BLOOD_Lymphoma	Regulation of lipoprotein particle clearance →	+0.141	+0.765	<.001	.003	3	3
BLOOD_Lymphoma	Interferon-mediated signaling pathway →	+0.065	+0.892	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,072 associations by consensus.

Response to superoxide by GIMAP8 expression — BLOOD_Lymphoma

Explore this box plot interactively →