GIMAP7

Across TCGA patient cohorts, GIMAP7 mutation is significantly associated with the RNA expression of many other genes, with 1,388 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GIMAP7-associated genes across cancer lineages are PSMC3IP, RC3H2, and MINDY2. Each is linked with GIMAP7 in more than 3 cancer types. Because this analysis shows association rather than direction, both GIMAP7-to-partner and partner-to-GIMAP7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PSMC3IP grouped by GIMAP7-low versus GIMAP7-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GIMAP7→partner) and Y-score (partner→GIMAP7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PSMC3IP →	+0.681	+3.608	<.001	.001	3	4
UCEC	RC3H2 →	+0.529	+2.708	.003	.003	3	3
UCEC	MINDY2 →	+0.516	+3.010	.006	<.001	3	3
UCEC	GOLGA1 →	+0.484	+3.042	<.001	<.001	3	3
UCEC	CDK11B →	+0.381	+2.847	.003	.001	3	3
BRCA	MIR6507 →	+0.359	+8.055	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,388 associations by consensus.

PSMC3IP by GIMAP7 expression — UCEC

Explore this box plot interactively →