GIMAP7

Across TCGA cell cohorts, GIMAP7 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible GIMAP7-associated genes across cancer lineages are TAS2R7, ZIM3, and ACER1. Each is linked with GIMAP7 in more than 1 cancer types. Because this analysis shows association rather than direction, both GIMAP7-to-partner and partner-to-GIMAP7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TAS2R7 grouped by GIMAP7-low versus GIMAP7-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GIMAP7→partner) and Y-score (partner→GIMAP7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	TAS2R7 →	+0.029	+5.643	<.001	.002	3	1
BLOOD_Lymphoma	ZIM3 →	+0.006	+6.247	<.001	<.001	3	1
LARGE_INTESTINE	ACER1 →	+0.096	+3.823	.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

TAS2R7 by GIMAP7 expression — BLOOD_Lymphoma

Explore this box plot interactively →