GIMAP6

Across TCGA patient cohorts, GIMAP6 mutation is significantly associated with the RNA expression of many other genes, with 1,096 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GIMAP6-associated genes across cancer lineages are SUPV3L1, FANCC, and LRR1. Each is linked with GIMAP6 in more than 1 cancer types. Because this analysis shows association rather than direction, both GIMAP6-to-partner and partner-to-GIMAP6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SUPV3L1 grouped by GIMAP6-low versus GIMAP6-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GIMAP6→partner) and Y-score (partner→GIMAP6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SUPV3L1 →	+0.425	+2.917	.004	.001	3	2
UCEC	FANCC →	+0.425	+3.202	.008	.009	3	2
UCEC	LRR1 →	+0.617	+3.343	.002	.005	3	2
UCEC	ENTR1 →	+0.502	+2.716	<.001	.003	3	2
UCEC	SAAL1 →	+0.534	+2.243	.003	.006	3	2
UCEC	DOLPP1 →	+0.530	+3.346	.003	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,096 associations by consensus.

SUPV3L1 by GIMAP6 expression — UCEC

Explore this box plot interactively →