GIMAP6

Across TCGA cell cohorts, GIMAP6 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,291 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible GIMAP6-associated GO terms across cancer lineages are Cardiac muscle cell action potential, Mitochondrion-endoplasmic reticulum membrane tethering, and Cardiac muscle cell contraction. Each is linked with GIMAP6 in more than 4 cancer types. Because this analysis shows association rather than direction, both GIMAP6-to-partner and partner-to-GIMAP6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cardiac muscle cell action potential grouped by GIMAP6-low versus GIMAP6-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GIMAP6→partner) and Y-score (partner→GIMAP6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Cardiac muscle cell action potential →	-0.082	-0.011	.002	.007	2	5
BLOOD_Leukemia	Mitochondrion-endoplasmic reticulum membrane tethering →	+0.078	+1.773	.003	.003	3	4
BLOOD_Leukemia	Cardiac muscle cell contraction →	-0.043	-1.222	.001	.001	3	4
LUNG_NSCLC_LUSC	Chromosome organization involved in meiotic cell cycle →	-0.136	-0.022	.004	.001	3	3
URINARY_TRACT	tRNA nucleoside ribose methylation →	+0.088	+0.015	<.001	<.001	2	4
CNS	Regulation of G2/M transition of mitotic cell cycle →	+0.032	+0.175	.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,291 associations by consensus.

Cardiac muscle cell action potential by GIMAP6 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →