Across TCGA pan-cancer cohorts, GIMAP5 Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated GIMAP5 data layer compared with 23 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher GIMAP5 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated GIMAP5 expression acts as an unfavorable survival marker.

COAD are the cancer types where GIMAP5 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Median	II,III,IV	0.097	0.855	<.001	51	view →

Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

Exploration

Same gene, other analysis: GIMAP5 tumor-vs-normal RNA expression · all GIMAP5 data types