Across TCGA patient cohorts, GIMAP5 mutation is significantly associated with the immune_cell of many other genes, with 5 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible GIMAP5-associated genes across cancer lineages are Mast cells, Myocytes, and Basophils. Each is linked with GIMAP5 in more than 1 cancer types. Because this analysis shows association rather than direction, both GIMAP5-to-partner and partner-to-GIMAP5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GIMAP5→partner) and Y-score (partner→GIMAP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	Mast cells →	+0.013	+1.580	.026	.031	3	2
SKCM	Myocytes →	+0.026	+1.321	.025	.015	3	2
SKCM	Basophils →	+0.117	+1.796	.015	.001	3	1
UCEC	Endothelial cells →	-0.044	-2.957	.045	.037	1	2
LUSC	Th1 cells →	+0.118	+3.181	.009	.010	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration

GIMAP5 survival (RNA) · tumor vs normal (RNA) · all GIMAP5 data types