Across TCGA cell cohorts, GIMAP5 mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible GIMAP5-associated genes across cancer lineages are F9, FIGLA, and CLDN24. Each is linked with GIMAP5 in more than 1 cancer types. Because this analysis shows association rather than direction, both GIMAP5-to-partner and partner-to-GIMAP5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GIMAP5→partner) and Y-score (partner→GIMAP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	F9 →	+0.019	+4.523	.005	.004	3	1
BLOOD_Lymphoma	FIGLA →	+1.227	+4.350	<.001	.005	3	1
BLOOD_Lymphoma	CLDN24 →	+1.884	+4.350	<.001	.005	3	1
BLOOD_Lymphoma	CBLN4 →	+0.071	+4.191	<.001	.007	3	1
LUNG_SCLC	IL3 →	+0.055	+5.029	<.001	.006	3	1
LUNG_SCLC	PRAMEF10 →	+1.180	+5.643	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

Exploration

GIMAP5 survival (RNA) · tumor vs normal (RNA) · all GIMAP5 data types