GIMAP4

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GIMAP4 protein abundance is significantly associated with the RNA expression of many other genes, with 18,065 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GIMAP4-associated genes across cancer lineages are CYTH4, MFNG, and GRAP2. Each is linked with GIMAP4 in more than 8 cancer types. Because this analysis shows association rather than direction, both GIMAP4-to-partner and partner-to-GIMAP4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GIMAP4 versus CYTH4 in GBM, with a Pearson correlation of 0.81.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GIMAP4→partner) and Y-score (partner→GIMAP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMCYTH4 →+1.121+0.774<.001<.00139
HNSCMFNG →+0.939+0.585<.001<.00139
HNSCGRAP2 →+0.921+0.612<.001<.00139
GBMNCF4 →+1.191+0.789<.001<.00139
HNSCCSF2RB →+1.221+0.712<.001<.00139
BRCAIL2RB →+1.236+0.523<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 18,065 associations by consensus.

GIMAP4 vs CYTH4 — GBM

Per-sample scatter of GIMAP4 vs CYTH4 in GBM (Pearson r = 0.81).

Explore this scatter interactively →

Exploration