GIMAP4

Across TCGA cell cohorts, GIMAP4 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,568 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GIMAP4-associated GO terms across cancer lineages are Sertoli cell development, Regulation of toll-like receptor 2 signaling pathway, and Hyperosmotic salinity response. Each is linked with GIMAP4 in more than 3 cancer types. Because this analysis shows association rather than direction, both GIMAP4-to-partner and partner-to-GIMAP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Sertoli cell development grouped by GIMAP4-low versus GIMAP4-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GIMAP4→partner) and Y-score (partner→GIMAP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Sertoli cell development →	-0.204	-0.050	<.001	.004	3	4
LUNG_NSCLC_LUAD	Regulation of toll-like receptor 2 signaling pathway →	-0.086	-0.017	<.001	.002	3	3
BLOOD_Leukemia	Hyperosmotic salinity response →	+0.151	+1.321	<.001	<.001	3	3
BLOOD_Leukemia	Cellular hyperosmotic salinity response →	+0.151	+1.321	<.001	<.001	3	3
BLOOD_Leukemia	Multicellular organismal-level chemical homeostasis →	-0.071	-1.134	.001	.001	3	3
BLOOD_Leukemia	Positive regulation of calcium ion transport into cytosol →	-0.232	-1.002	.006	.007	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,568 associations by consensus.

Sertoli cell development by GIMAP4 expression — LUNG_SCLC

Explore this box plot interactively →