GIMAP3P

Across TCGA pan-cancer cohorts, GIMAP3P RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated GIMAP3P data layer.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher GIMAP3P RNA is associated with better overall survival. In most high-consensus cancer types, elevated GIMAP3P expression acts as an unfavorable survival marker, although some lineages such as BLCA and HNSC show a favorable association.

BLCA, HNSC, and BRCA are the cancer types where GIMAP3P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	OS	Tertile	All	0.801	0.677	.002	90	view →
HNSC	OS	Quartile	All	0.489	0.315	<.001	66	view →
BRCA	DFS	Median	III,IV	0.551	0.419	.003	36	view →
SKCM	OS	Tertile	All	0.918	0.846	.008	33	view →
OV	DFS	Quartile	All	0.465	0.352	.009	32	view →
KIRC	DFS	Tertile	All	0.801	0.532	.004	27	view →
STAD	DFS	Tertile	IV	0.861	0.143	.005	27	view →
LUSC	OS	Quartile	III,IV	0.367	0.841	.004	24	view →
THCA	DFS	Quartile	IV	0.910	0.489	.009	13	view →
CHOL	DFS	Tertile	All	1.000	0.232	.011	12	view →
KICH	OS	Median	All	1.000	0.791	.014	12	view →
ESCA	OS	Quartile	III,IV	0.668	0.349	.019	11	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

GIMAP3P–BLCA (OS)

Open the BLCA breakdown →