GIMAP2

Across TCGA pan-cancer cohorts, GIMAP2 Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated GIMAP2 data layer compared with 25 for mass-spec protein and 4 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher GIMAP2 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated GIMAP2 expression acts as an unfavorable survival marker, although some lineages such as LUAD show a favorable association.

COAD, LUAD, and SKCM are the cancer types where GIMAP2 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	All	0.443	0.785	<.001	24	view →
LUAD	DFS	Median	All	1.000	0.657	.034	6	view →
SKCM	OS	Median	IV	0.415	0.861	.014	4	view →
HNSC	DFS	Median	All	0.184	0.603	.044	3	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

GIMAP2–COAD (DFS)

Open the COAD breakdown →