GIMAP2

Across TCGA patient cohorts, GIMAP2 protein abundance is significantly associated with the RNA expression of many other genes, with 15,030 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GIMAP2-associated genes across cancer lineages are CD3D, CD74, and HLA-DQA1. Each is linked with GIMAP2 in more than 6 cancer types. Because this analysis shows association rather than direction, both GIMAP2-to-partner and partner-to-GIMAP2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GIMAP2 versus CD3D in HNSC, with a Pearson correlation of 0.29.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GIMAP2→partner) and Y-score (partner→GIMAP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CD3D →	+1.419	+0.617	.003	<.001	3	7
HNSC	CD74 →	+1.578	+0.913	<.001	<.001	3	7
HNSC	HLA-DQA1 →	+1.034	+0.631	<.001	<.001	3	7
HNSC	SAMHD1 →	+0.791	+0.661	<.001	<.001	3	6
HNSC	LPXN →	+0.824	+0.563	<.001	<.001	3	6
LSCC	BIN2 →	+0.861	+0.623	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,030 associations by consensus.

GIMAP2 vs CD3D — HNSC

Explore this scatter interactively →