GIMAP2

Across TCGA cell cohorts, GIMAP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,791 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GIMAP2-associated GO terms across cancer lineages are Basement membrane disassembly, Antigen processing and presentation of exogenous peptide antigen via MHC class Ib, and Positive regulation of chromatin binding. Each is linked with GIMAP2 in more than 13 cancer types. Because this analysis shows association rather than direction, both GIMAP2-to-partner and partner-to-GIMAP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Basement membrane disassembly grouped by GIMAP2-low versus GIMAP2-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GIMAP2→partner) and Y-score (partner→GIMAP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Basement membrane disassembly →	+1.335	+0.986	<.001	.001	3	14
SOFT_TISSUE	Antigen processing and presentation of exogenous peptide antigen via MHC class Ib →	+0.241	+1.242	<.001	<.001	3	13
LIVER	Positive regulation of chromatin binding →	+0.262	+1.000	<.001	.001	3	13
URINARY_TRACT	Regulation of tolerance induction dependent upon immune response →	+1.657	+1.827	<.001	<.001	3	12
LIVER	Cytolysis in another organism →	+1.723	+1.060	.002	<.001	3	12
LIVER	Antigen processing and presentation of endogenous peptide antigen via MHC class I →	+0.261	+0.823	.001	.005	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,791 associations by consensus.

Basement membrane disassembly by GIMAP2 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →