Across TCGA patient cohorts, GIMAP1 mutation is significantly associated with the RNA expression of many other genes, with 1,011 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GIMAP1-associated genes across cancer lineages are RBM22P13, HIKESHIP1, and BAG3. Each is linked with GIMAP1 in more than 2 cancer types. Because this analysis shows association rather than direction, both GIMAP1-to-partner and partner-to-GIMAP1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GIMAP1→partner) and Y-score (partner→GIMAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RBM22P13 →	+0.014	+2.065	<.001	.002	3	3
COAD	HIKESHIP1 →	+0.269	+2.567	.002	.009	3	2
UCEC	BAG3 →	+0.796	+3.584	<.001	.002	3	2
UCEC	SEC13 →	+0.386	+3.362	.006	.005	3	2
UCEC	ZMYND19 →	+0.486	+2.839	.001	.001	3	2
UCEC	ING2 →	+0.506	+3.949	.004	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,011 associations by consensus.

Exploration

GIMAP1 survival (RNA) · tumor vs normal (RNA) · all GIMAP1 data types