Across TCGA patient cohorts, GIMAP1 mutation is significantly associated with the total protein of many other genes, with 27 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible GIMAP1-associated genes across cancer lineages are TIGAR, Cyclin-B1, and ACC1. Each is linked with GIMAP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GIMAP1-to-partner and partner-to-GIMAP1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GIMAP1→partner) and Y-score (partner→GIMAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	TIGAR →	+0.110	+3.186	.030	.009	3	2
SKCM	Cyclin-B1 →	+0.395	+2.012	.013	.017	3	2
UCEC	ACC1 →	+0.389	+2.820	.026	.035	3	1
UCEC	p62 Lck ligand →	+0.447	+3.584	.004	.002	3	1
UCEC	VHL →	-1.087	-3.459	<.001	.005	3	1
UCEC	YAP_pS127 →	+0.321	+3.169	.040	.019	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 27 associations by consensus.

Exploration

GIMAP1 survival (RNA) · tumor vs normal (RNA) · all GIMAP1 data types